Neuropathic pain is one of the most difficult types of chronic pain to treat. For patients across Chapel Hill and the Triangle who have not found relief with conventional therapies, Ketamine Wellness Institute offers IV ketamine therapy delivered under physician supervision. Since 2017, our clinic has specialized in safe, evidence-based ketamine care. Every infusion is overseen by a physician anesthesiologist, ensuring both comfort and safety.
Ketamine blocks NMDA receptors, which are central to the transmission of pain signals in the nervous system. By dampening these pathways, ketamine can reduce the intensity of neuropathic pain and, in some cases, help reset how the nervous system processes pain. Patients who have lived with constant discomfort sometimes report meaningful improvements in quality of life after beginning a course of infusions.
Care begins with a comprehensive consultation where our physicians review your medical history, pain pattern, and prior treatments. If IV ketamine is appropriate, patients usually begin with a stabilization series of infusions. Sessions for neuropathic pain often last longer than those for mood disorders—typically two to three hours—because higher dosing and extended administration are required.
During the infusion, you will be in a private treatment room equipped with a recliner and dimmable lights. Vital signs are monitored throughout, and staff remain available to manage side effects such as nausea. Afterward, patients stay on site for recovery before heading home with their driver.
IV ketamine may be considered for patients with neuropathic pain who have not improved with standard medications. Conditions may include diabetic neuropathy, post-herpetic neuralgia, chemotherapy-induced neuropathy, complex regional pain syndrome (CRPS), and other forms of nerve-related pain. Suitability depends on your medical history, current prescriptions, and overall safety profile.
Our physicians take time to evaluate each case, ensuring treatment is appropriate before proceeding.
IV ketamine for neuropathic pain is an off-label use and is generally not covered by insurance. Our staff will provide a clear overview of pricing and discuss available payment options during your consultation, so you know exactly what to expect.
Conditions Treated
5915 Farrington Rd Suite 105
Chapel Hill, NC 27517